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inhibitor of metalloproteinase (IMP) or tissue inhibitor of metalloproteinase (TIMP)
Presumably TIMP-1 has been frequently referred to as TIMP.
Specific
metalloproteinase inhibitor 1; Tissue inhibitor of metalloproteinases; TIMP-1; erythroid-potentiating activity; EPA; fibroblast collagenase inhibitor; collagenase inhibitor (TIMP1, CLGI)
metalloproteinase inhibitor 2; Tissue inhibitor of metalloproteinases 2; TIMP-2; CSC-21K (TIMP2)
metalloproteinase inhibitor 3; Tissue inhibitor of metalloproteinases 3; TIMP-3; protein MIG-5 (TIMP3)
metalloproteinase inhibitor 4; Tissue inhibitor of metalloproteinases 4; TIMP-4 (TIMP4)
General
enzyme inhibitor
glycoprotein
Properties
SIZE: entity length = 200 aa
MOTIF: cysteine-rich region
MOTIF: cysteine residue {X+0}
MODIFICATION: cysteine residue {X+X3}
cysteine residue {X+X1}
MODIFICATION: cysteine residue {X+X4}
cysteine residue {X+X2}
MODIFICATION: cysteine residue {X+X5}
cysteine residue {X+X3}
MODIFICATION: cysteine residue {X+0}
cysteine residue {X+X4}
MODIFICATION: cysteine residue {X+X1}
cysteine residue {X+X5}
MODIFICATION: cysteine residue {X+X2}
cysteine residue {X+X6}
MODIFICATION: cysteine residue {X+X11}
cysteine residue {X+X7}
MODIFICATION: cysteine residue {X+X8}
cysteine residue {X+X8}
MODIFICATION: cysteine residue {X+X8}
cysteine residue {X+X9}
MODIFICATION: cysteine residue {X+X10}
cysteine residue {X+X10}
MODIFICATION: cysteine residue {X+X9}
cysteine residue {X+X11}
MODIFICATION: cysteine residue {X+X6}
FOR-BINDING-OF: metalloprotease
glycosylation site
References
- Banda MJ et al
Secreted inhibitors of metalloproteinases (IMPs) that are
distinct from TIMP.
Matrix Suppl 1:294 1992
PMID: 1480040