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thyroid C-cell hyperplasia; C-cell proliferative disorder

Etiology: - age-associated [2] - medullary thyroid carcinoma - multiple endocrine neoplasia II and IIB - multiple endocrine neoplasia IIB Pathology: - may be same as premalignant medullary thyroid carcinoma or carcinoma in situ Genetics: - inherited autosomal dominant form [3] Laboratory: - serum calcitonin - ret genotyping for medullary thyroid carcinoma

Related

C-cell

General

thyroid disease hyperplasia

References

  1. Guyetant S et al C-Cell Hyperplasia and Medullary Thyroid Carcinoma: Clinicopathological and Genetic Correlations in 66 Consecutive Patients Mod Pathol 2003;16(8):756-763 http://www.nature.com/modpathol/journal/v16/n8/full/3880836a.html
  2. Gibson WG et al Age-associated C-cell hyperplasia in the human thyroid Am J Pathol. 1982 March; 106(3): 388-393 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1916228/
  3. LiVolsi VA Editorial: C Cell Hyperplasia/Neoplasia J Clin Endocrinoland Metab 1997, 82(1):39-41 http://jcem.endojournals.org/content/82/1/39.full.pdf