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thymosin beta-15A; NB thymosin beta; thymosin-like protein 8 (TMSB15A, TMSL8, TMSNB)
Function:
- plays a role in organization of the cytoskeleton
- binds to & sequesters actin monomers (G actin) & thus inhibits actin polymerization (putative)
Structure: belongs to the thymosin beta family
Compartment: cytoplasm, cytoskeleton (putative)
Expression:
- neuroblastoma-specific
- down-regulated by TGFB1
General
thymosin-beta
Properties
SIZE: entity length = 45 aa
MW = 5 kD
COMPARTMENT: cytoplasm
MOTIF: acetylation site
SITE: N-TERMINUS
EFFECTOR-BOUND: acetyl
Database Correlations
OMIM 601587
UniProt P0CG34
Pfam PF01290
LOCUS-LINK correlations
References
UniProt :accession P0CG34