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thymidylate kinase; dTMP kinase (DTYMK, CDC8, TMPK, TYMK)
Function:
- catalyzes the conversion of dTMP to dTDP
- pyrimidine metabolism; dTTP biosynthesis
ATP + dTMP = ADP + dTDP
Structure:
- belongs to the thymidylate kinase family
General
kinase or ATP-phosphotransferase
Properties
SIZE: entity length = 212 aa
MW = 24 kD
MOTIF: acetylation site
SITE: N-TERMINUS
EFFECTOR-BOUND: acetyl
ATP-binding site
NAME: ATP-binding site
SITE: 13-20
kinase domain
MOTIF: ATP-binding site
NAME: ATP-binding site
Database Correlations
OMIM 188345
UniProt P23919
Pfam PF02223
Entrez Gene 1841
Kegg hsa:1841
ENZYME 2.7.4.9
References
UniProt :accession P23919