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thrombin inhibitor
Indications:
- anticoagulation
Adverse effects:
- hepatotoxicity (ximelagatran)
Overdose
- activated prothrombin concentrate complex 50-100 units/kg IV
Mechanism of action:
- inhibition of thrombin
Interactions
drug interactions
drug adverse effects of antithrombotic agent(s)
Related
thrombin; coagulation factor IIa
Specific
argatroban (Novastan)
dabigatran (Pradaxa)
desirudin (Iprivask)
lepirudin; hirudin (Refludan)
vorapaxar (Zontivity)
ximelagatran (Exanta)
General
enzyme inhibitor
pharmaceutical anticoagulant
References
- Medical Knowledge Self Assessment Program (MKSAP) 16,
American College of Physicians, Philadelphia 2012