THO complex subunit 3 (Tho3, TEX1 homolog, THOC3)

Function: 1) component of THO/TREX complex 2) may physically link proteins that function in transcription & in RNA export Structure: contains 6 WD repeats Compartment: nucleus (probable) Genetics: - there are two almost identical copies of this gene on chromosome 5q35 - one copy is frameshifted & unlikely to encode a functional protein

General

protein subunit WD repeat protein family

Properties

SIZE: MW = 39 kD entity length = 351 aa COMPARTMENT: cell nucleus MOTIF: WD repeat {53-94} WD repeat {97-137} WD repeat {139-178} WD repeat {180-221} WD repeat {222-261} WD repeat {264-303}

Database Correlations

OMIM 606929 UniProt Q96J01 Pfam PF00400 Kegg hsa:8432

References

UniProt :accession Q96J01