THO complex subunit 2 (Tho2, THOC2)

Function: 1) component of THO/TREX complex 2) may physically link proteins that function in transcription & in RNA export Structure: belongs to the THOC2 family Compartment: nucleus (probable) Alternative splicing: named isoforms=2

General

phosphoprotein protein subunit

Properties

SIZE: entity length = 1478 aa MW = 170 kD COMPARTMENT: cell nucleus MOTIF: nuclear translocation signal {808-813} Ser phosphorylation site {S1107} lysine-rich region {1149-1476} MOTIF: lysine residue (SEVERAL) Thr phosphorylation site {T1174} Ser phosphorylation site {S1249} Thr phosphorylation site {T1270} Ser phosphorylation site {S1275} Ser phosphorylation site {S1302} Thr phosphorylation site {T1328} Ser phosphorylation site {S1333} Ser phosphorylation site {S1371} Ser phosphorylation site {S1401}

Database Correlations

OMIM 300395 UniProt Q8NI27 Kegg hsa:5718

References

UniProt :accession Q8NI27