THO complex subunit 1 (Tho1, nuclear matrix protein p84, THOC1, HPR1)

Function: 1) component of the THO/TREX complex 2) binds to hypophosphorylated form of RB1 Structure: - contains 1 death domain Compartment: nucleus, nuclear speckle, nucleoplasm, nuclear matrix

General

phosphoprotein protein subunit

Properties

SIZE: MW = 76 kD entity length = 657 aa COMPARTMENT: cell nucleus MOTIF: Ser phosphorylation site {S560} death domain NAME: death domain SITE: 570-653

Database Correlations

OMIM 606930 UniProt Q96FV9 Pfam PF00531

References

UniProt :accession Q96FV9