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thiol; sulhydryl compound; mercaptan

A compound that contains the functional group -SH, the sulfur analogue of an alcohol group -OH. The term mercaptan comes from the Latin mercurius captans, meaning 'laying hold of mercury,' because the -SH group binds tightly to the element mercury. Many thiols are colorless liquids often with strong & repulsive odor. Thiols bind strongly to skin proteins, & are responsible for the intolerable, persistent odor produced by the spraying of skunks. Cysteine (Cys) is the thiol of proteins.

Specific

1,4-dithiothreitol; 1,4-dimercapato-2,3-butanediol (DTT, Cleland's reagent) 2-mercaptobenzothiazole (Captax, Mebetizole) 4-phosphopantothenoylcysteine amifostine (Ethyol, ethiofos, gammaphos, amifostinum) captopril (Capoten) coenzyme A cysteamine; 2-aminoethanethiol (Cystagon) cysteine dimercaprol (BAL, British anti-Lewisite, dithioglycerol, Sulfactin, Dimersol, Antoxol, Panobal) homocysteine lipoate; thioctic acid; thioctate; alpha-lipoic acid mesna; 2-mercaptoethane sulfonate; 2-sulfanylethanesulfonic acid (Mesnex, Uromitexan, Mistabronco) pantetheine penicillamine (Cuprimine, Depen) pyrithione; 2-pyridinethiol-1-oxide thiorphan (Lopac-T-6031, Prestwick-694) thiosalicylate tiopronin; alpha-mercaptopropionylglycine (Tiola) unithiol (2,3-dithiopropanesulfate, 2,3-dimercapto-1-propane sulfonate)

General

sulfur compound

References

- Wikepedia, thiol http://en.wikipedia.org/thiol