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thiol; sulhydryl compound; mercaptan
A compound that contains the functional group -SH, the sulfur analogue of an alcohol group -OH.
The term mercaptan comes from the Latin mercurius captans, meaning 'laying hold of mercury,' because the -SH group binds tightly to the element mercury.
Many thiols are colorless liquids often with strong & repulsive odor. Thiols bind strongly to skin proteins, & are responsible for the intolerable, persistent odor produced by the spraying of skunks.
Cysteine (Cys) is the thiol of proteins.
Specific
1,4-dithiothreitol; 1,4-dimercapato-2,3-butanediol (DTT, Cleland's reagent)
2-mercaptobenzothiazole (Captax, Mebetizole)
4-phosphopantothenoylcysteine
amifostine (Ethyol, ethiofos, gammaphos, amifostinum)
captopril (Capoten)
coenzyme A
cysteamine; 2-aminoethanethiol (Cystagon)
cysteine
dimercaprol (BAL, British anti-Lewisite, dithioglycerol, Sulfactin, Dimersol, Antoxol, Panobal)
homocysteine
lipoate; thioctic acid; thioctate; alpha-lipoic acid
mesna; 2-mercaptoethane sulfonate; 2-sulfanylethanesulfonic acid (Mesnex, Uromitexan, Mistabronco)
pantetheine
penicillamine (Cuprimine, Depen)
pyrithione; 2-pyridinethiol-1-oxide
thiorphan (Lopac-T-6031, Prestwick-694)
thiosalicylate
tiopronin; alpha-mercaptopropionylglycine (Tiola)
unithiol (2,3-dithiopropanesulfate, 2,3-dimercapto-1-propane sulfonate)
General
sulfur compound
References
- Wikepedia, thiol
http://en.wikipedia.org/thiol