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thioflavin T stain; basic yellow 1 stain

A stain used to detect amyloid. Positive staining results in a specific yellow fluorescence. Tissue sections are 1st immersed in alum-hematoxylin to quench nuclear fluorescence, then stained with thioflavin T. Early diffuse amyloid deposits may not stain well.

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thioflavin T; basic yellow 1

General

tissue stain

References

  1. Stedman's Medical Dictionary 27th ed, Williams & Wilkins, Baltimore, 1999
  2. Selkoe DJ. Alzheimer's disease: genes, proteins, and therapy. Physiol Rev. 2001 Apr;81(2):741-66. Review. PMID: 11274343