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therapy-related leukemia
Genetics:
- chromosomal translocation t(3;11)(p21;q23) involving NCKIPSD with MLL is found in therapy-related leukemia
- chromosomal translocation t(16;21)(q24;q22) involving CBFA2T3 with RUNX1 is found in therapy-related myeloid malignancies; translocation forms a RUNX1-CBFA2T3 fusion protein
General
leukemia
References
UniProt :accession Q9NZQ3