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THAP domain-containing protein 1 (THAP1)
Function:
- pro-apoptopic protein
- potentiates both serum-withdrawal & TNF-induced apoptosis
- interacts with PAWR
Structure: contains 1 THAP domain
Compartment: nucleus, nucleoplasm, PML nuclear bodies
General
THAP domain-containing protein (THAP)
Properties
SIZE: MW = 25 kD
entity length = 213 aa
COMPARTMENT: cell nucleus
MOTIF: THAP {1-81}
MOTIF: Zinc finger
NAME: Zinc finger
SITE: 5-57
EFFECTOR-BOUND: Zn+2
coiled coil {139-190}
Database Correlations
UniProt Q9NVV9
Pfam PF05485
References
UniProt :accession Q9NVV9