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thalidomide plus dexamethasone (thal/dex)
Indications:
1) multiple myeloma
2) myelodysplastic syndrome
Dosage:
- thalidomide 200 mg plus 40 mg dexamethasone
- days 1-4, 9-12, 17-20; repeat cycle every 28 days
General
antineoplastic combination (combination chemotherapy)
References
- Rajkumar SV et al,
Phase III clinical trial of thalidomide plus dexamethasone
compared with dexamethasone alone in newly diagnoses multiple
myeloma: A clinical trial coordinated by the Eastern Cooperative
Oncology Group.
J Clin Oncol 2006; 24:231
PMID: 16365178
Richardson P and Anderson K
Thalidomide and dexamethasone: A new standard of care for
initial therapy in multiple myeloma.
J Clin Oncol 2006l 24:334
PMID: 16365174
- UpToDate 14.1
http://www.utdol.com