thyroid adenoma-associated protein; gene inducing thyroid adenomas protein (THADA, GITA, KIAA1767)

Structure: belongs to the THADA family Alternative splicing: named isoforms=5 Expression: - expressed in pancreas, adrenal medulla, thyroid, adrenal cortex, testis, thymus, small intestine & stomach Pathology: - chromosomal translocations t(2;3)(p21;p25) & t(2;7)(p21;p15) involving THADA have been observed in benign thyroid adenomas; the fusion events probably result in truncated THADA proteins

Properties

GENERAL: uncharacterized protein SIZE: entity length = 1953 aa MW = 220 kD FORM: thyroid adenoma-associated protein MOTIF: lysine-rich region {4-7} MOTIF: lysine residue (SEVERAL) coiled coil {886-918} alanine-rich region {1529-1532} MOTIF: alanine residue (SEVERAL)

Database Correlations

UniProt Q6YHU6 Kegg hsa:6389

References

UniProt :accession Q6YHU6