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tendon xanthoma; tendinous xanthoma

Etiology: - familial hypercholesterolemia (pathognomonic) [2] - cerebrotendinous xanthomatosis - sitosterolemia Clinical manifestations: - lipid deposition within tendons, ligaments & fascia - smooth, firm, lobulated nodules over extensor surfaces, especially over extensor tendons of hands, elbows, knees, & Achilles tendon Laboratory: - LDL cholesterol elevated

General

xanthoma

References

  1. Medical Knowledge Self Assessment Program (MKSAP) 15, 18. American College of Physicians, Philadelphia 2009, 2018.
  2. NEJM Knowledge+