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telomeric repeat amplification protocol (TRAP)
Specimen: urine
Indications:
- screening for bladder cancer (investigational) [1] may be useful for screening high-risk patients
Differential diagnosis:
- bladder cancer
Interpretation:
- reflects telomerase activity in voided urine
General
polymerase chain reaction (PCR)
References
- Sanchini MA, Gunelli R, Nanni O, Bravaccini S, Fabbri C,
Sermasi A, Bercovich E, Ravaioli A, Amadori D, Calistri D.
Relevance of urine telomerase in the diagnosis of bladder cancer.
JAMA. 2005 Oct 26;294(16):2052-6.
PMID: 16249419