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targeted error correction sequencing

Clinical significance: - developed to detect circulating cell-free DNA from many early tumors [1] - method of cell-free DNA in plasma

General

DNA sequencing; next-generation sequencing

References

  1. Phallen J, Sausen M, Adleff V et al Direct detection of early-stage cancers using circulating tumor DNA. Science Translational Medicine. 16 Aug 2017: 9(403):eaan2415 PMID: 28814544 http://stm.sciencemag.org/content/9/403/eaan2415