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transcription initiation factor TFIID subunit 11; TFIID subunit p30-beta; transcription initiation factor TFIID 28 kD subunit; TAF(II)28; TAFII-28; TAFII28 (TAF11, TAF2I, PRO2134, p28TFIID)
Function:
- component of TFIID, both TFIID-alpha & TFIID-beta (see TFIID)
- interacts with TAF13 both in vitro & intracellularly
- also interacts directly with TBP
- phosphorylated upon DNA damage, probably by ATM or ATR
Structure:
- TBP & TAFII18 bind to distinct domains of TAFII28
- belongs to the TAF11 family
Compartment: nucleus
General
phosphoprotein
transcription factor IID subunit
Properties
SIZE: entity length = 211 aa
MW = 23 kD
COMPARTMENT: cell nucleus
MOTIF: acetylation site
SITE: N-TERMINUS
EFFECTOR-BOUND: acetyl
Ser phosphorylation site {S60}
Database Correlations
OMIM 600772
UniProt Q15544
Pfam PF04719
Entrez Gene 6882
Kegg hsa:6882
References
- UniProt :accession Q15544
- NIEHS-SNPs
http://egp.gs.washington.edu/data/taf11/
Component-of
transcription factor IID (TFIID)