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transcription initiation factor TFIID subunit 10; STAF28; transcription initiation factor TFIID 30 kD subunit; TAF(II)30; TAFII-30; TAFII30 (TAF10, TAF2A, TAF2H, TAFII30)
Function:
- component of TFIID complex, PCAF histone acetylase complex & TBP-free TAFII complex (TFTC)
- interacts with TAF3
- monomethylated at Lys-189 by SETD7, leading to increase its affinity for RNA polymerase 2
Structure:
- [KR]-[STA]-K motif is specifically recognized by the SETD7 methyltransferase
- belongs to the TAF10 family
Compartment: nucleus
General
transcription factor IID subunit
Properties
SIZE: entity length = 218 aa
MW = 22 kD
COMPARTMENT: cell nucleus
MOTIF: [KR]-[STA]-K {187-189}
Database Correlations
OMIM 600475
UniProt Q12962
Pfam PF03540
Entrez Gene 6881
Kegg hsa:6881
References
- UniProt :accession Q12962
- NIEHS-SNPs
http://egp.gs.washington.edu/data/taf10/
Component-of
TAF complex (SMAT)