TACTICS-TIMI trial

The study evaluated 18 patients with unstable angina or non-ST- segment elevated myocardial infarction. Patients were randomized to: a) early angiography (within 48 hours), or b) conservative measures (angiography & revascularization if recurrent ischemia at rest or with provocative testing, despite medical therapy) Patients receiving early angiography had significantly reduced rates of combined: 1) death 2) recurrent myocardial infarction 3) rehospitalization for acute coronary syndrome Patients with elevation of troponin levels were found to benefit from early angiography. Also see VANQWISH trial.

Related

coronary angiography myocardial infarction (MI); heart attack VANQWISH trial

References

Journal Watch 22(2):13, 2002 Morrow et al JAMA 286:2405, 2001 Quinn & Moliterna JAMA 286:2461, 2001