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tabes dorsalis
Syphilis of the spinal cord.
Clinical manifestations:
1) neurologic manifestations
a) sudden pains in trunk & lower limbs
b) paresthesias
c) positive Rhomberg sign
d) lost vibratory sensation
e) absent deep tendon reflexes (DTR)
f) ataxia accentuated in the dark
2) abdominal pain & vomiting with relaxed abdomen (tabes crisis)
3) urinary incontinence
4) impotence
5) eye manifestations
a) visual impairment
b) Argyl Robertson pupil
c) ocular palsies
6) Charcot joints
Laboratory:
1) positive serologic tests for syphilis
2) elevated serum globulin
3) lumbar puncture
a) elevated cerebrospinal fluid (CSF) pressure
b) positive CSF VDRL
General
neurosyphilis (dementia paralytica, syphilitic paresis)
References
DeGowin & DeGowin's Diagnostic Examination, 6th edition,
RL DeGowin (ed), McGraw Hill, NY 1994, pg 937