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chromosomal translocation t7p34:9q32

- chromosomal translocation t(7;9)(q34;q32) involving TAL2 with TCRB is associated with T-cell acute lymphoblastic leukemia (T-ALL)

Properties

GENERAL: chromosomal translocation RELATED: tal2 gene T-cell receptor [TCR]-beta subunit gene FORM: t7p34:9q32 LOCUS: human chromosome-7 Q34 human chromosome-9 Q32 PATHOLOGY: precursor T-lymphoblastic leukemia/lymphoma ABERRANT-GENE: T-cell receptor [TCR]-beta subunit gene tal2 gene

References

Harrison's Principles of Internal Medicine, 14th ed. Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 519