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syntaxin
2 syntaxins A & B are 84% identical & expressed only in the CNS. They may function in docking synaptic vesicles near Ca+2 channels at presynaptic active zones. Syntaxins associate with synaptotagmin.
Interactions
molecular events
Related
synaptotagmin
Specific
syntaxin-1A; syntaxin-A; neuron-specific antigen HPC-1 (STX1A, STX1)
syntaxin-1B; syntaxin-1B1; syntaxin-1B2 (STX1B STX1B1 STX1B2)
syntaxin-2; epimorphin (STX2, EPIM, STX2A, STX2B, STX2C)
syntaxin-3; syntaxin-3A; syntaxin-3B (STX3, STX3A, STX3B)
syntaxin-4; renal carcinoma antigen NY-REN-31 (STX4, STX4A)
syntaxin-5 (STX5, STX5A)
syntaxin-6 (STX6)
syntaxin-7 (STX7)
syntaxin-8 (STX8)
syntaxin-10; syn10 (STX10 SYN10)
syntaxin-11 (STX11)
syntaxin-12 (STX12)
syntaxin-16; syn16 (STX16)
syntaxin-17 (STX17, KAT01814)
syntaxin-18; cell growth-inhibiting gene 9 protein (STX18)
syntaxin-19 (STX19)
General
SNARE [soluble NSF attachment receptor] protein (SNARE, SNAP receptor)
Properties
COMPARTMENT: intracellular vesicle
MOTIF: transmembrane domain
References
- Sollner T, Whiteheart SW, Brunner M et al
SNAP receptors implicated in vesicle targeting and fusion.
Nature. 1993 Mar 25;362(6418):318-24.
PMID: 8455717
- Bennett MK, Calakos N, Scheller RH.
Syntaxin: a synaptic protein implicated in docking of synaptic
vesicles at presynaptic active zones.
Science. 1992 Jul 10;257(5067):255-9.
PMID: 1321498
Component-of
molecular complex