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sulfotransferase 6B1; ST6B1; thyroxine sulfotransferase (SULT6B1)
Function:
- specifically a sulfotransferase activity towards thyroxine
- role in the metabolism of thyroxine
3'-phosphoadenylyl sulfate + thyroxine = adenosine 3',5'-bisphosphate + thyroxine-sulfate
Structure: belongs to the sulfotransferase 1 family
Compartment: cytoplasm (putative)
Alternative splicing:
- named isoforms=2
- additional isoforms seem to exist
Expression:
- specifically expressed in kidney & testis
General
sulfotransferase
Properties
SIZE: entity length = 303 aa
MW = 35 kD
COMPARTMENT: cytoplasm
MOTIF: histidine residue {H118}
active site
Database Correlations
UniProt Q6IMI4
Pfam PF00685
Entrez Gene 391365
Kegg hsa:391365
ENZYME 2.8.2.n2
References
UniProt :accession Q6IMI4