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sublingual grass pollen extract (Oralair)
Also see sublingual immunotherapy
Indications:
- first sublingual allergen extract approved for treatment of allergic rhinitis & allergic conjunctivitis due to grass pollen for patients age 10-65 years [1]
Dosage:
- sublingual once daily tablet
- observe first dose in clinician's office
Adverse effects:
- most common
- itching & swelling in the mouth
- throat irritation
- serious: anaphylaxis (boxed warning)
Mechanism of action:
- antigen sensitization
- mix of five grass pollens:
- Kentucky Blue Grass
- Orchard Grass
- Perennial Rye Grass
- Sweet Vernal Grass
- Timothy grass
Related
sublingual immunotherapy (SLIT)
General
sublingual allergen extract
References
- FDA News Release: April 2, 2014
FDA approves first sublingual allergen extract for the treatment
of certain grass pollen allergies.
http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm391458.htm