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Subdoligranulum

Epidemiology: - a genus of endogenous intestinal bacteria Laboratory: - obligate anaerobe Pathology: - may be implicated in rheumatoid arthritis [1]

General

Ruminococcaceae (Oscillospiraceae)

Properties

KINGDOM: monera DIVISION: SCHIZOMYCETES

References

  1. Gever J Momentum Builds for Microbiome as RA Trigger. Second study published in a week's time to implicate intestinal bacteria in joint pathology. MedPage Today October 26, 2022 https://www.medpagetoday.com/rheumatology/arthritis/101435 - Chriswell ME Lefferts AR, Clay MR et al Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum. Science Translational Medicine. 2022. 14(688):eabn5166. Oct 26 PMID: 36288282 https://www.science.org/doi/10.1126/scitranslmed.abn5166
  2. Van Hul M, Le Roy T, Prifti E et al From correlation to causality: the case of Subdoligranulum. Gut Microbes. 2020; 12(1): 1849998. PMID: 33323004 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744154/