stibogluconate; Sb[V] antimony sodium gluconate; solustibosan; solyusurmin; myostibin; pentostam; solustin; stibanate; stibanose; stibatin

Sodium stibogluconate. Pentavalent antimonial Sb[V]. Indications: - Leishmaniasis a) available from CDC (404 639-3670) b) 20 mg Sb[V]/kg IM/IV for 20 days cutaneous leishmaniasis & 28 days visceral leishmaniasis Adverse effects: 1) myalgia 2) arthralgia 3) fatigue 4) hepatotoxicity 5) chemical pancreatitis 6) electrocardiographic abnormalities 7) increasingly common as treatment progresses 8) generally do not limit therapy 9) effects are reversible

References

Harrison's Principles of Internal Medicine, 14th ed. Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 1188