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stanozolol; androstanazol (Winstrol)
Tradename: Winstrol. DEA-controlled substance: class 3.
Indications:
- prophylactic use against angioedema
- aplastic anemia [2]
- antithrombin deficiency [2]
Contraindications:
- pregnancy
Caution: avoid use in patients with severe hepatic insufficiency
Dosage:
1) adults:
a) start: 2 mg TID
b) reduce to maintenance of 2 mg QD or 2 mg QOD after 1-3 months
2) children:
a) < 6 years: 1 mg QD
b) 6-12 years: 2 mg QD
Tabs: 2 mg.
Adjust dose with hepatic insufficiency.
Adverse effects:
Male (postpubertal):
1) common (> 10%)
- acne, gynecomastia, bladder irritability, priapism
2) less common (1-10%)
- insomnia, chills, decreased libido, hepatic dysfunction, nausea, diarrhea, prostatic hypertrophy (elderly), iron-deficiency anemia, suppression of clotting factors
3) uncommon (< 1%)
- hepatic necrosis, hepatocellular carcinoma
Male (prepubertal):
1) common (> 10%)
- acne, virilism
2) less common (1-10%)
- chills, insomnia, hyperpigmentation, diarrhea, nausea, iron-deficiency anemia, suppression of clotting factors
3) uncommon (< 1%)
- hepatic necrosis, hepatocellular carcinoma
Female:
1) common (> 10%)
- virilism
2) less common (1-10%)
- chills, insomnia, hypercalcemia, nausea, diarrhea, iron-deficiency anemia, suppression of clotting factors, hepatic dysfunction
3) uncommon (< 1%)
- hepatic necrosis, hepatocellular carcinoma
Interactions
drug adverse effects of androgens
Related
angioneurotic edema; angioedema; atrophedema; Bannister's disease; Milton's disease; Quincke's disease; periodic or Quincke's edema; giant urticaria or hives; urticaria gigans, gigantea, or tuberosa.
General
androgen or anabolic steroid
Properties
MISC-INFO: pregnancy-category X
Database Correlations
PUBCHEM correlations
References
- Kaiser Permanente Northern California Regional Drug
Formulary, 1998
- Deprecated Reference