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squamous cell carcinoma of the vulva
Epidemiology:
1) uncommon
2) 1-5% of genital cancers in women
3) diagnosis generally made in 6th to 7th decade of life
Pathology:
1) 75% associated with HPV
2) 40% of invasive vulvar carcinoma associated with HPV
Clinical manifestations:
1) vulvar itching is the most common presenting complaint
2) lesions are generally unifocal
3) lesions may be ulcerated, friable or indurated
Laboratory: biopsy of persistent vulvar lesions
Management:
1) excision
2) prophylaxis: HPV vaccine
General
squamous cell carcinoma (SCC)
vulvar cancer
References
- Medical Knowledge Self Assessment Program (MKSAP) 11, American
College of Physicians, Philadelphia 1998
- Judson PL, Habermann EB, Baxter NN, Durham SB, Virnig BA.
Trends in the incidence of invasive and in situ vulvar carcinoma.
Obstet Gynecol. 2006 May;107(5):1018-22.
PMID: 16648405
- Geriatrics at your Fingertips, 13th edition, 2011
Reuben DB et al (eds)
American Geriatric Society
- National Cancer Institute
Vulvar Cancer -Health Professional Version
https://www.cancer.gov/types/vulvar/hp