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squamous cell carcinoma of the tongue

Etiology: - risk factors - papillomavirus - smoking Pathology: - verrucous carcinoma (variant of squamous cell carcinoma) - grows slowly - locally destructive - rarely metastasizes Clinical manifestations: - glossodynia (tongue pain) - dysphagia - dysarthria Management: - methotrexate to reduce the size of the tumor prior to surgical excision (case report) [1] - prognosis: 5-year survival is 50% [2]

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tongue

General

tongue neoplasm squamous cell carcinoma of the mouth

References

  1. Hassona Y, Scully C Images in clinical medicine. Verrucous tongue lesion. N Engl J Med 2015; 372:2049. May 21, 2015 PMID: 25992749 http://www.nejm.org/doi/full/10.1056/NEJMicm1408030
  2. Albuquerque RP, Richards A. IMAGES IN CLINICAL MEDICINE. Squamous-Cell Carcinoma of the Tongue. N Engl J Med. 2016 Jun 23;374(25):e32. PMID: 27332922 http://www.nejm.org/doi/full/10.1056/NEJMicm1513456