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sporadic cretinism
Etiology:
1) developmental failure in thyroid gland development (sporadic athyrotic cretinism)
2) biosynthetic defect in thyroid hormone formation
General
cretinism (congenital hypothyroidism)
References
Cotran et al Robbins Pathologic Basis of Disease,
5th ed. W.B. Saunders Co, Philadelphia, PA 1994 pg 1125