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spondylolisthesis (listhesis, olisthesis)
Subluxation of the body of a vertebra on the vertebra below. (at least 3 mm at the lumbar spine)
Etiology:
- trauma
- motor vehicle accident
Epidemiology:
- prevalence of lumbar spondylolisthesis 8.7%
Pathology:
1) sacrum may become more vertical, impairing hip extension
2) neurologic involvement is uncommon because vertebra slips anteriorly, away from spinal cord & nerve roots
Clinical manifestations:
1) prominent spinal process may be palpable
2) impaired gait, flexed knee, flexed hip (Phalen-Dickson sign)
3) leg pain upon prolonged standing or walking [9]
4) exercise in sitting position (cycling) generally tolerated
5) neurologic involvement is uncommon
Radiology:
- standing flexion-extension radiographs of lumbar spine
- subluxation a vertebral body on the vertebra below
- images
- radiograph of C2 [8]
- computed tomography through C2 (image) [8]
Complications:
- spinal stenosis
Differential diagnosis:
- sciatica
Management:
1) treatment is controversial
2) chiropractic manipulation is considered to be helpful
3) physical therapy
4) lumbar bracing to prevent hyperextension
5) rest
6) non-steroidal anti-inflammatory agents
7) referral to orthopedic surgeon [4]
8) indications for surgical fusion
a) intractable pain
b) growing child with slippage > 50%
9) addition of fusion to decompression in patients with lumbar spinal stenosis & spondylolisthesis may have small benefit [7]
- decompression + fusion no better than decompression alone [11]
10) epidural glucocorticoids dont seem to effect surgical or non-surgical management of degenerative lumbar spondylolisthesis[10]
Related
back pain
spondylitis
spondyloarthropathy (HLA B27-associated arthritis, seronegative spondyloarthropathy)
spondylolysis
spondylosis
Specific
anterolisthesis
retrolisthesis
spondyloptosis
General
sign/symptom
References
- Vogt MT, Rubin DA, Palermo L, Christianson L, Kang JD,
Nevitt MC, Cauley JA.
Lumbar spine listhesis in older African American women.
Spine J. 2003 Jul-Aug;3(4):255-61.
PMID: 14589183
- Iguchi T, Wakami T, Kurihara A, Kasahara K, Yoshiya S,
Nishida K.
Lumbar multilevel degenerative spondylolisthesis: radiological
evaluation and factors related to anterolisthesis and
retrolisthesis.
J Spinal Disord Tech. 2002 Apr;15(2):93-9.
PMID: 11927816
- Pellengahr C, Pfahler M, Kuhr M, Hohmann D.
Influence of facet joint angles and asymmetric disk collapse
on degenerative olisthesis of the cervical spine.
Orthopedics. 2000 Jul;23(7):697-701.
PMID: 10917245
- UpToDate 14.1
http://www.utdol.com
- Weinstein JN et al,
Surgical versus nonsurgical treatment for lumbar degenerative
spondylolisthesis
N Engl J Med 2007, 356:2257
- Diagnosis and treatment of degenerative lumbar spondylolisthesis.
North American Spine Society
PMID: 10917245
http://www.spine.org/Documents/Spondylolisthesis_Clinical_Guideline.pdf
- Ghogawala Z, Dziura J, Butler WE et al
Laminectomy plus Fusion versus Laminectomy Alone for Lumbar
Spondylolisthesis.
N Engl J Med 2016; 374:1424-1434. April 14, 2016
PMID: 27074067
http://www.nejm.org/doi/full/10.1056/NEJMoa1508788
- Khelifi A, Saadaoui F. (case presentation)
Traumatic Spondylolisthesis of the Axis.
N Engl J Med 2017; 376:1782May 4, 2017
PMID: 28467872
http://www.nejm.org/doi/full/10.1056/NEJMicm1405867
- Geriatric Review Syllabus, 10th edition (GRS10)
Harper GM, Lyons WL, Potter JF (eds)
American Geriatrics Society, 2019
- Gerling MC et al.
Epidural steroid injections for management of degenerative
spondylolisthesis: Little effect on clinical outcomes in
operatively and nonoperatively treated patients.
J Bone Joint Surg Am 2020 Aug 5; 102:1297
PMID: 32769595
- Austevoll IM et al.
Decompression with or without fusion in degenerative lumbar spondylolisthesis.
N Engl J Med 2021 Aug 5; 385:526.
PMID: 34347953
- Lau KKL et al.
Demographic, surgical, and radiographic risk factors for symptomatic
adjacent segment disease after lumbar fusion: A systematic review and
meta-analysis.
J Bone Joint Surg Am 2021 Aug 4; 103:1438.
PMID: 34166276
Images
images related to spondylolisthesis