Search
spindle nuclear transfer
Indications:
- inherited mitochondrial disease in women (Leigh syndrome)
Procedure:
- the nucleus of a donor egg is removed
- the nucleus from the mother's egg is placed into the donor egg
- the father's sperm fertilizes the egg, which contains the mother's nuclear DNA & the donor's mitochondrial DNA
- the fertilized egg is then implanted in the mother [1]
General
assisted reproduction technology (ART)
References
- Young K, Fairchild DG, Di Francesco L
Report: First Baby Born with DNA from 3 People
Physician's First Watch, Sept 28, 2016
David G. Fairchild, MD, MPH, Editor-in-Chief
Massachusetts Medical Society
http://www.jwatch.org
- Hamzelou J
Exclusive: World's first baby born with new "3 parent"
technique.
New Scientist. Sept 27, 2016
https://www.newscientist.com/article/2107219-exclusive-worlds-first-baby-born-with-new-3-parent-technique/