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sperm protein associated with the nucleus on the X chromosome C (nuclear-associated protein SPAN-Xc, cancer-testis-associated protein CTp11, SPANXC)
Structure: belongs to the SPAN-X family
Compartment:
- cytoplasm, nucleus
- associated with nuclear craters.
Expression:
- detected in testis, in round & elongating spermatids
Pathology:
- expressed in melanoma & bladder carcinoma
General
sperm protein associated with the nucleus on the X chromosome (SPAN-X family, SPANX)
Properties
SIZE: MW = 11 kD
entity length = 97 aa
COMPARTMENT: cytoplasm
cell nucleus
MOTIF: nuclear translocation signal {37-45}
glutamate-rich region {83-86}
MOTIF: glutamate residue (SEVERAL)
Database Correlations
OMIM 300330
UniProt Q9NY87
Pfam PF07458
References
UniProt :accession Q9NY87