sodium tetradecyl sulfate (Sotradecol, Texapon K, Niaproof 4, Obliterol)

Tradename: Sotradecol. (tetradecyl sulfate, Na+) Indications: 1) treatment of small, uncomplicated varicose veins of the lower extremities 2) endoscopic sclerotherapy in the management of bleeding esophageal varices Dosage: 1) 0.5-2 mL of 1% (5-20 mg) for small veins IV 2) 0.5-2 mL of 3% (15-60 mg) for medium or large veins (IV) Injection: 1% (2 mL), 3% (2 mL). Adverse effects: 1) not common (1-10%) - headache, urticaria, mucosal lesions, nausea/vomiting, discoloration at the site of injection, pain, ulceration at the site of injection, sloughing & tissue necrosis following extravasation, pulmonary edema 2) uncommon (< 1%) - esophageal perforation, hives, asthma

References

Kaiser Permanente Northern California Regional Drug Formulary, 1998