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small lymphocytic lymphoma
Chronic lymphocytic leukemia & small lymphocytic lymphoma are the same disease, the first predominates in peripheral blood, the second predominates in lymph nodes.
Immunophenotype:
- CD5(+), CD20(+/-), CD23(+)
Genetics:
- trisomy 12
Management:
- see chronic lymphocytic leukemia
- idelalisib for treatment failure
Interactions
disease interactions
Specific
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma (B-CLL)
extranodal marginal zone B-cell lymphoma; low grade B-cell lymphoma of MALT [mucosa associated lymphoid tissue] type, MALToma
lymphoplasmacytic lymphoma/immunocytoma
nodal marginal zone B-cell lymphoma
small B-cell lymphoma
splenic marginal zone B-cell lymphoma
T-cell prolymphocytic leukemia (TPLL)
General
small-cell lymphoma
References
- Medical Knowledge Self Assessment Program (MKSAP) 15, 18.
American College of Physicians, Philadelphia 2009, 2018.