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Sm (Smith) protein/antigen

Smith antigen, target of SLE Ab, may be family of proteins. Binding of Sm protein to snRNA & cap trimethylation required for nuclear translocation.

Related

Sm (Smith) Ab in serum SmIg Ag in tissue

Specific

small nuclear ribonucleoprotein associated protein N (SmN) [tissue-specific slicing factor] (SnRPN) small nuclear ribonucleoprotein Sm D1; Sm-D1; Sm-D autoantigen; snRNP core protein D1 (SNRPD1) small nuclear ribonucleoprotein Sm D2; snRNP core protein D2; Sm-D2 (SNRPD2) small nuclear ribonucleoprotein Sm D3; snRNP core protein D3; Sm-D3 (SNRPD3) small nuclear ribonucleoprotein [snRNP] polypeptide SmB/B'

General

splicing factor; snRNP-associated protein

Properties

COMPARTMENT: cell nucleus MOTIF: RNA-binding motif FOR-BINDING-OF: ribonucleic acid

References

- Nigg EA, Baeuerle PA, Luhrmann R. Nuclear import-export: in search of signals and mechanisms. Cell. 1991 Jul 12;66(1):15-22. Review. No abstract available. PMID: 1712670