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Zinc transporter ZIP10 (solute carrier family 39 member 10, SLC39A10, KIAA1265, ZIP10)
Function: may act as a zinc-influx transporter
Structure: belongs to the ZIP transporter (TC 2.A.5) family
Compartment: membrane (putative)
Pathology:
- high levels of expression are correlated with invasiveness in several breast cancer lines
General
glycoprotein
membrane protein
phosphoprotein
solute carrier family 39 (SLC39, SLC39A)
Properties
SIZE: entity length = 831 aa
MW = 94 kD
COMPARTMENT: cellular membrane
MOTIF: signal sequence {1-25}
histidine-rich region {26-40}
MOTIF: histidine residue (SEVERAL)
histidine-rich region {101-197}
MOTIF: histidine residue (SEVERAL)
N-glycosylation site {N139}
N-glycosylation site {N198}
N-glycosylation site {N339}
transmembrane domain {411-431}
transmembrane domain {438-458}
histidine-rich region {458-483}
MOTIF: histidine residue (SEVERAL)
transmembrane domain {495-515}
Ser phosphorylation site {S546}
Ser phosphorylation site {S591}
histidine-rich region {607-656}
MOTIF: histidine residue (SEVERAL)
transmembrane domain {687-707}
transmembrane domain {732-752}
transmembrane domain {759-779}
transmembrane domain {801-821}
Database Correlations
OMIM 608733
UniProt Q9ULF5
Pfam PF02535
References
UniProt :accession Q9ULF5