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solute carrier family 35 member C2 (SLC35C2, ovarian cancer overexpressed gene 1 protein, C20orf5, OVCOV1, CGI-15)
Function:
- role in the cellular response to tissue hypoxia (putative)
Structure:
- belongs to the TPT transporter family, SLC35C subfamily
Compartment: membrane (putative)
Alternative splicing: named isoforms=2
Expression:
- ubiquitously
- level of expression is tissue dependent
- expressed in hypoxic trophoblast cells
Pathology:
- overexpressed in ovarian cancer
General
glycoprotein
phosphoprotein
solute carrier family 35 (SLC35, SLC35A, SLC35B, SLC35C, SLC35D, SLC35E)
transmembrane 8 protein
Properties
SIZE: MW = 40 kD
entity length = 365 aa
COMPARTMENT: cellular membrane
MOTIF: transmembrane domain {14-34}
transmembrane domain {42-62}
N-glycosylation site {N102}
transmembrane domain {104-124}
transmembrane domain {136-156}
transmembrane domain {158-178}
transmembrane domain {202-222}
transmembrane domain {242-262}
transmembrane domain {294-316}
Ser phosphorylation site {S335}
Database Correlations
UniProt Q9NQQ7
Pfam PF03151
Kegg hsa:5100
References
UniProt :accession Q9NQQ7