superkiller viralicidic activity 2-like 2; ATP-dependent helicase SKIV2L2 (SKIV2L2, KIAA0052, Mtr4)

Function: - may be involved in pre-mRNA splicing - associated with the RNA exosome complex & involved in 3'processing of the 7S pre-RNA to the mature 5.8S rRNA - associated with the RNA exosome complex - identified in the spliceosome C complex Structure: - belongs to the helicase family, SKI2 subfamily - contains 1 helicase ATP-binding domain - contains 1 helicase C-terminal domain Compartment: nucleus, nucleolus

Properties

SIZE: entity length = 1042 aa MW = 118 kD COMPARTMENT: cell nucleus MOTIF: acetylation site SITE: N-TERMINUS EFFECTOR-BOUND: acetyl helicase NAME: helicase SITE: 148-304 MOTIF: ATP-binding site NAME: ATP-binding site SITE: 161-168 DEAD/H box NAME: DEAD/H box SITE: 252-255 Helicase C-terminal {405-577}

Database Correlations

UniProt P42285 PFAM correlations Entrez Gene 23517 Kegg hsa:23517 ENZYME 3.6.4.13

References

UniProt :accession P42285