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silent atrial fibrillation; atrial high-rate episodes
- atrial high-rate episodes represent a potentially heterogenous group of atrial arrhythmias detected by implantable cardiac devices
- prior atrial fibrillation on surface electrocardiogram
Clinical trials:
- ARTESiA trial
- CHA2DS2-VASc score > 4, apixaban resulted in 1.3 fewer episodes of stroke or systemic embolism per 100 patient-years without significant increase in bleeding
- CHA2DS2-VASc score of <= 4 or less, reduction in stroke or systemic embolism withh apixaban not statistically significant
General
atrial fibrillation (AF)
References
- Kirchhof P et al.
Anticoagulation with edoxaban in patients with atrial high-rate episodes.
N Engl J Med 2023 Aug 25; [e-pub].
PMID: 37622677
https://www.nejm.org/doi/10.1056/NEJMoa2303062
- Wong JA, Conen D, Van Gelder IC et al.
Progression of device-detected subclinical atrial fibrillation
and the risk of heart failure.
J Am Coll Cardiol 2018 Jun 12; 71:2603.
PMID: 29880119
- Glotzer TV.
The cacophony of silent atrial fibrillation.
J Am Coll Cardiol 2018 Jun 12; 71:2612.
PMID: 29880120