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sialadenosis (sialosis)
Etiology:
- unknown
- may be due to inappropriate autonomic nervous system stimulation
- may be associated with endocrine disorders (diabetes mellitus)
- may be associated with nutritional disorders (pellagra, bulimia)
- may be associated with medications (thioridazine, isoprenaline)
Epidemiology:
- commonly presents in persons 20-60 years of age
- equal prevalence between males & females
Pathology:
- noninflammatory disorder
- parotid acinar enlargement with hyperdense cytoplasmic granules
Clinical manifestations:
- bilateral parotid gland enlargement
- soft, non-tender, bilaterally enlarged parotid glands
Special laboratory:
- tissue biopsy
Differential diagnosis:
- parotitis
Related
sialadenitis
General
salivary gland disease
References
- Wilson M, Pandey S
StatPearls. NCBI Bookshelf. Aug 28, 2022
https://www.ncbi.nlm.nih.gov/books/NBK560735/