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small G protein signaling modulator 1; RUN & TBC1 domain-containing protein 2 (SGSM1, RUTBC2, KIAA1941)
Function:
- rab GTPase-activating protein (putative)
- interacts with RAB3A, RAB4A, RAB5A, RAB8A, RAB11A, RAP1A, RAP1B, RAP2A and RAP2B
- no interaction with RAB27A Strucure:
- belongs to the RUTBC family
- contains 1 Rab-GAP TBC domain
- contains 1 RUN domain
Compartment: Golgi, trans-Golgi network
Alternative splicing: named isoforms=3
Expression: mainly expressed in brain, heart & testis
General
rab GTPase-activating protein (rab-GAP)
Properties
SIZE: MW = 130 kD
entity length = 1148 aa
MOTIF: RUN {36-190}
rab-GAP domain
NAME: rab-GAP domain
SITE: 617-1081
Database Correlations
UniProt Q2NKQ1
PFAM correlations
References
UniProt :accession Q2NKQ1