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splicing factor 3B subunit 2 (spliceosome associated protein 145, SAP 145, SF3b150, pre-mRNA splicing factor SF3b 145 kD subunit, SF3B2)


General

protein subunit splicing factor; snRNP-associated protein

Properties

SIZE: entity length = 872 aa MW = 98 kD COMPARTMENT: cell nucleus MOTIF: SAP {1-35} proline-rich region SITE: 68-73 MOTIF: proline residue (SEVERAL) proline-rich region SITE: 81-90 MOTIF: proline residue (SEVERAL) proline-rich region SITE: 106-109 MOTIF: proline residue (SEVERAL) proline-rich region SITE: 226-230 MOTIF: proline residue (SEVERAL) Ser phosphorylation site {S266} glutamate-rich region {269-274} MOTIF: glutamate residue (SEVERAL) Ser phosphorylation site {S284} Ser phosphorylation site {S286} Thr phosphorylation site {T288} lysine-rich region {308-312} MOTIF: lysine residue (SEVERAL) Ser phosphorylation site {S320} Ser phosphorylation site {S337} Ser phosphorylation site {S339} Ser phosphorylation site {S393} Ser phosphorylation site {S408} Ser phosphorylation site {S412} Ser phosphorylation site {S413} glutamate-rich region {676-679} MOTIF: glutamate residue (SEVERAL) glutamate-rich region {697-703} MOTIF: glutamate residue (SEVERAL) Ser phosphorylation site {S755} Thr phosphorylation site {T757}

Database Correlations

OMIM 605591 UniProt Q13435 PFAM correlations Kegg hsa:1099

References

UniProt :accession Q13435

Component-of

spliceosome C complex