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splicing factor 3B subunit 2 (spliceosome associated protein 145, SAP 145, SF3b150, pre-mRNA splicing factor SF3b 145 kD subunit, SF3B2)
General
protein subunit
splicing factor; snRNP-associated protein
Properties
SIZE: entity length = 872 aa
MW = 98 kD
COMPARTMENT: cell nucleus
MOTIF: SAP {1-35}
proline-rich region
SITE: 68-73
MOTIF: proline residue (SEVERAL)
proline-rich region
SITE: 81-90
MOTIF: proline residue (SEVERAL)
proline-rich region
SITE: 106-109
MOTIF: proline residue (SEVERAL)
proline-rich region
SITE: 226-230
MOTIF: proline residue (SEVERAL)
Ser phosphorylation site {S266}
glutamate-rich region {269-274}
MOTIF: glutamate residue (SEVERAL)
Ser phosphorylation site {S284}
Ser phosphorylation site {S286}
Thr phosphorylation site {T288}
lysine-rich region {308-312}
MOTIF: lysine residue (SEVERAL)
Ser phosphorylation site {S320}
Ser phosphorylation site {S337}
Ser phosphorylation site {S339}
Ser phosphorylation site {S393}
Ser phosphorylation site {S408}
Ser phosphorylation site {S412}
Ser phosphorylation site {S413}
glutamate-rich region {676-679}
MOTIF: glutamate residue (SEVERAL)
glutamate-rich region {697-703}
MOTIF: glutamate residue (SEVERAL)
Ser phosphorylation site {S755}
Thr phosphorylation site {T757}
Database Correlations
OMIM 605591
UniProt Q13435
PFAM correlations
Kegg hsa:1099
References
UniProt :accession Q13435
Component-of
spliceosome C complex