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thyroid-stimulating immunoglobulin (TSI) in serum

Indications: - suspected Graves disease - suspected euthyroid Graves ophthalmopathy - pregnancy complicated by Graves disease - atypical fluctuating hypothyroidism or hyperthyroidism Clinical significance: - antibody stimulating TSH receptors in thyroid, autonomous with regard to negative feedback from T3, T4

Related

anti-thyrotropin Graves disease (Basedow's disease, exothalmic goiter) thyrotropin receptor antibody; TSH receptor antibody

General

thyrotropin (TSH) receptor Ab in serum

References

  1. Medical Knowledge Self Assessment Program (MKSAP) 15, American College of Physicians, Philadelphia 2009
  2. Thyroid Stimulating Immunoglobulin Laboratory Test Directory ARUP: 99430 Laboratory Test Directory ARUP: 3002287 - TSH Receptor Antibody Laboratory Test Directory ARUP: 2002734