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septin-11 (SEPT11)
Function:
- involved in cytokinesis (putative)
- may assemble into a multicomponent structure
Structure: belongs to the septin family
Pathology:
- a chromosomal translocation t(4;11)(q21;q23) involving SEPT11 with MLL/HRX may be a cause of chronic neutrophilic leukemia
General
septin
Properties
SIZE: MW = 49 kD
entity length = 429 aa
MOTIF: GTP-binding site
SITE: 48-55
coiled coil {320-415}
Database Correlations
UniProt Q9NVA2
Pfam PF00735
References
UniProt :accession Q9NVA2