Search
secretin stimulation test
Indications:
- chronic pancreatitis
Normal range:
1) > 15 meq of bicarbonate in 30 minutes
2) > 80 meq/L in at least 1 specimen collected over 1 hour
* 1 meq = 1 mmol
Procedure:
- performed by intubating the duodenum & measuring the pancreatic secretion of bicarbonate in response to IV infusion of secretin 1.0 U/kg & or cholecystokinin
- 4.0-5.0 U/kg of secretin is used in the augmented secretin test
Clinical significance:
- although, the secretin stimulation test is the most sensitive test for diagnosing chronic pancreatitis, it is cumbersome, unpleasant & has fallen from favor
Related
malabsorption
secretin (SCT)
General
special chemistry test
References
- Clinical Diagnosis & Management by Laboratory Methods,
19th edition, J.B. Henry (ed), W.B. Saunders Co.,
Philadelphia, PA. 1996, pg 530
- Medical Knowledge Self Assessment Program (MKSAP) 11, American
College of Physicians, Philadelphia 1998
Components
gastrin in serum post secretin stimulation