squamous cell carcinoma antigen recognized by T-cells 2 (SART-2, SART2)

Compartment: membrane Expression: - ubiquitously expressed - expressed in kidney & ovary > brain, colon & thymus Pathology: - expressed in renal cell carcinomas, brain tumors, & in a part of melanomas & adenocarcinomas from organs other than the breast - expressed in squamous cell carcinomas (SCC), glioma, & some adenocarcinoma cell lines, but not in breast cancer cell lines or any normal tissues (at protein level)

General

glycoprotein membrane protein

Properties

SIZE: MW = 110 kD entity length = 958 aa COMPARTMENT: cellular membrane MOTIF: signal sequence {1-22} N-glycosylation site {N642} transmembrane domain {903-923} transmembrane domain {934-954}

Database Correlations

OMIM 605942 UniProt Q9UL01

References

UniProt :accession Q9UL01