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sin3-associated peptide, 30kD (SAP30, histone deacetylase complex subunit SAP30, sin3 corepressor complex subunit SAP30)

Function: 1) protein subunit of sin3 repressor complex 2) functional recruitment of Sin3-histone deacetylase complex (HDAC) to a specific subset of N-CoR corepressor complexes 3) transcription repression by N-CoR 4) interacts with SIN3A, SIN3B, HDAC2, NCOR1, HDAC1, HCFC Compartment: nucleus Expression: - expressed in all tissues tested - highest levels in pancreas, ovary, PBL, spleen, thymus - lowest levels in brain, placenta, lung, kidney

Related

sin3-protein

General

protein subunit

Properties

SIZE: MW = 30 kD

Database Correlations

OMIM 603378 UniProt O75446

References

  1. OMIM :accession 603378
  2. UniProt :accession O75446

Component-of

sin3 repressor complex