SAPK substrate protein 1; UBA/UBX 33.3 kDa protein (SAKS1, UBXN1)

Function: - component of a NGLY1/SAKS1/AMFR/VCP/RAD23B complex - role in ubiquitin-proteasome systems - interacts with HOMER2 - interacts directly with VCP - binds polyubiquitin Structure: - contains 1 UBA domain - contains 1 UBX domain Compartment: cytoplasm Alternative splicing: named isoforms=2

Properties

SIZE: MW = 33 kD entity length = 297 aa COMPARTMENT: cytoplasm MOTIF: UBA domain {1-42} coiled coil {87-172} Ser phosphorylation site {S200} UBX {211-293}

Database Correlations

UniProt Q04323 PFAM correlations

References

UniProt :accession Q04323